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Sedation and Delirium in the ICU

Source: N Engl J Med 2014;370:444-54.

Definition of delirium (DSM-IV)
Four domains of delirium: disturbance of consciousness, change in cognition, development over a short period, and fluctuation.

Definition of delirium (NIH)
Sudden severe confusion and rapid changes in brain function that occur with physical or mental illness.

Medications and Assessment





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